Description

Ethyl (R)-2-Hydroxybutanoate is a high-purity chiral ester, a key intermediate in the synthesis of optically active compounds. Its defined stereochemistry is critical for producing pharmaceuticals and fine chemicals with high enantiomeric purity and desired biological activity. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and flavor & fragrance industries, where precise molecular configuration dictates product efficacy and safety.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for synthesizing active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, pesticides, and plant growth regulators for enhanced activity and environmental safety.
• Flavor and Fragrance Ingredient: Serves as a precursor for creating specific, high-value chiral flavor compounds and aroma chemicals.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Employed in the development of chiral catalysts and ligands for stereoselective chemical transformations.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway research.
• Fine Chemical Production: Acts as a versatile intermediate for manufacturing specialty chemicals requiring the (R)-2-hydroxybutanoate moiety.

Basic Information

Product Name	Ethyl (R)-2-Hydroxybutanoate
CAS No.	87172-81-4
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	(R)-Ethyl 2-Hydroxybutyrate; (R)-2-Hydroxybutyric Acid Ethyl Ester; Ethyl (R)-2-Hydroxybutyrate; (R)-Ethyl 2-Hydroxybutanoate; (R)-α-Hydroxybutyric Acid Ethyl Ester; D-Ethyl 2-Hydroxybutyrate; (2R)-2-Hydroxybutanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl (R)-2-Hydroxybutanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) verification by HPLC or GC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and compliance with your research or cGMP production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.