Description

Adenine-13C is a stable isotope-labeled analog of the fundamental purine base adenine, where the carbon-13 isotope is incorporated at a specific position. This precise labeling is critical for advanced analytical techniques, enabling researchers to track metabolic pathways and quantify biomolecules with high accuracy. It is an essential reagent for scientists in pharmaceutical research, clinical diagnostics, and metabolic studies who require reliable, high-purity isotopic tracers.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analysis of nucleic acids, nucleotides, and related metabolites.
• Metabolic Pathway Tracing: Enables the study of purine synthesis, salvage pathways, and nucleotide turnover in cell culture and in vivo models.
• Pharmaceutical Drug Development: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies for drugs targeting nucleotide metabolism.
• Clinical Diagnostic Assays: Serves as a critical component in the development of high-sensitivity assays for genetic disorders and metabolic diseases.
• Biochemical Research: Facilitates NMR-based structural and dynamic studies of nucleic acids and protein-nucleic acid complexes.
• Isotope Dilution Analysis: Provides accurate quantification of adenine and its derivatives in complex biological matrices.

Basic Information

Product Name	Adenine-13C
CAS No.	86967-48-8
Molecular Formula	C413CH5N5
Molecular Weight	136.11 g/mol
Synonyms	6-Aminopurine-13C; 1H-Purin-6-amine-13C; Vitamin B4-13C; 9H-Purin-6-amine-13C; Adenine (13C-labeled); [13C]Adenine; Stable Isotope Labeled Adenine; 13C-Labeled Adenine
EINECS	Contact for details

Quality Control

Every batch of Adenine-13C is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and isotopic enrichment meet the exacting requirements of research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as chemical purity (by HPLC), isotopic purity, and specific position of labeling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.