Description

Cefoperazone Monobactam CAS NO 86702-45-6 is a high-purity chemical intermediate, primarily recognized for its role in the synthesis of advanced β-lactam antibiotics. Its significance lies in providing a reliable and consistent building block for pharmaceutical R&D and manufacturing, ensuring the structural integrity of the final active pharmaceutical ingredient (API). This compound is essential for manufacturers and research institutions focused on developing and producing next-generation antibacterial agents to address evolving microbial resistance.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of Cefoperazone sodium and related third-generation cephalosporin antibiotics.
• Antibacterial Research & Development: Serves as a critical scaffold for medicinal chemists exploring new derivatives with enhanced efficacy against resistant bacterial strains.
• API Manufacturing: Used in controlled process chemistry for the large-scale GMP production of finished antibiotic APIs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Biochemical Studies: Utilized in microbiological and pharmacological research to study β-lactamase inhibition and antibiotic mechanisms of action.

Basic Information

Product Name	Cefoperazone Monobactam
CAS No.	86702-45-6
Molecular Formula	C25H27N9O8S2
Molecular Weight	645.67 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-[D(-)-α-(4-Ethyl-2,3-dioxo-1-piperazinylcarbonylamino)-phenylacetamido]-3-(1-methyl-1H-tetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic Acid; Cefoperazone Acid; Cefoperazone Free Acid; CPZ Monobactam
EINECS	Contact for details

Quality Control

Our Cefoperazone Monobactam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.