Description

2-Methyl-2-Propanol, T-[1-14C] is a carbon-14 labeled isotopologue of tert-Butyl alcohol, a versatile tertiary alcohol. This radiolabeled compound is essential for conducting precise metabolic and environmental fate studies, providing critical data on compound degradation, distribution, and transformation. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and environmental science sectors for advanced analytical and tracer applications.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in pharmaceutical research to study the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and their metabolites.
• Environmental Fate Studies: Applied in agrochemical and environmental research to track the degradation, persistence, and movement of chemical compounds in soil, water, and biological systems.
• Analytical Chemistry Reference Standard: Serves as a critical internal standard or reference material in advanced analytical techniques like Liquid Scintillation Counting (LSC) and accelerator mass spectrometry (AMS).
• Organic Synthesis Intermediate: Employed in the synthesis of more complex carbon-14 labeled molecules for research purposes, leveraging its reactive tertiary alcohol and methyl groups.
• Biochemical Research: Facilitates studies on enzyme mechanisms and biochemical pathways where the fate of the tert-butyl group needs to be monitored with high sensitivity.

Basic Information

Product Name	2-Methyl-2-Propanol, T-[1-14C]
CAS No.	86634-48-2
Molecular Formula	C4H10O (with 14C at the T-methyl position)
Molecular Weight	~74.12 g/mol (exact mass depends on 14C enrichment)
Synonyms	tert-Butyl alcohol-14C; 2-Methyl-2-propanol-1-14C; TBA-14C; 2-Methylpropan-2-ol-14C; tert-Butanol-14C; (CH3)3C14OH; 1,1-Dimethylethanol-14C; Trimethylcarbinol-14C
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2-Propanol, T-[1-14C] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our quality commitment includes comprehensive testing via HPLC, radiochemical purity analysis, and specific activity determination. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant Good Manufacturing Practice (GMP) guidelines for radioactive materials.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated area. For optimal stability, it is recommended to store the product at 2-8°C. Follow all applicable local and international regulations for the safe storage of radioactive materials.

Specification

Item	Specification
Appearance	Clear, Colorless Liquid
Identification (IR)	Conforms to Structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC)	≥ 99%
Specific Activity	50-60 mCi/mmol (Customizable)
Solvent	Ethanol or as specified
Concentration	1.0 mCi/mL (Customizable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.