Description

2-(1,3-Dioxolan-2-Yl)Ethyltriphenylphosphonium Bromide is a specialized organophosphorus compound, specifically a phosphonium salt, that serves as a versatile reagent in advanced organic synthesis. Its primary value lies in its role as a key Wittig reagent precursor, enabling the efficient construction of complex olefins and fine chemical intermediates. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex molecule assembly.

Application

• Wittig Reaction Reagent: A crucial precursor for generating stabilized ylides used in the synthesis of alkenes, particularly for constructing complex, multi-functional olefin structures found in active pharmaceutical ingredients (APIs) and natural products.
• Pharmaceutical Intermediate: Employed in the synthesis of key chiral and achiral intermediates for drug discovery and development, especially in creating carbon-carbon double bonds under mild conditions.
• Agrochemical Synthesis: Used in the production of advanced pesticide and herbicide intermediates where specific alkene geometry is critical for biological activity.
• Material Science Research: Acts as a building block in the development of novel organic materials, including liquid crystals and functional polymers, via olefination reactions.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry laboratories focused on new synthetic methodologies involving phosphorus chemistry.

Basic Information

Product Name	2-(1,3-Dioxolan-2-Yl)Ethyltriphenylphosphonium Bromide
CAS No.	86608-70-0
Molecular Formula	C25H28BrO2P
Molecular Weight	471.36 g/mol
Synonyms	[2-(1,3-Dioxolan-2-yl)ethyl]triphenylphosphonium bromide; 2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide; (2-(1,3-Dioxolan-2-yl)ethyl)triphenylphosphonium bromide; Triphenyl[2-(1,3-dioxolan-2-yl)ethyl]phosphonium bromide; Phosphonium, [2-(1,3-dioxolan-2-yl)ethyl]triphenyl-, bromide (1:1); 86608-70-0; Acetal-protected hydroxyethyltriphenylphosphonium bromide
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dioxolan-2-Yl)Ethyltriphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including NMR (¹H, ¹³C, ³¹P), HPLC for purity, and Karl Fischer titration for moisture content to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) with full spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.