Description

(2R,3R)-2-Hydroxy-3-Methylpentanoic Acid CAS NO 86540-81-0 is a high-purity, chiral hydroxy acid building block essential for the synthesis of complex organic molecules. Its defined stereochemistry makes it a critical intermediate for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and cardiovascular drug development.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a building block for advanced materials, liquid crystals, and specialty polymers requiring high optical purity.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies, metabolic pathway analysis, and the development of chiral catalysts.
• Flavor & Fragrance Industry: Potential use as a precursor for synthesizing chiral flavor compounds and aroma chemicals.
• Asymmetric Synthesis: A valuable starting material or auxiliary in stereoselective organic synthesis for academic and industrial R&D.

Basic Information

Product Name	(2R,3R)-2-Hydroxy-3-Methylpentanoic Acid
CAS No.	86540-81-0
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	(2R,3R)-2-Hydroxy-3-methylpentanoic acid; (2R,3R)-3-Methyl-2-hydroxypentanoic acid; D-three-3-Methyl-2-hydroxypentanoic acid; (2R,3R)-2-Hydroxy-3-methylvaleric acid; (2R,3R)-HMVA; (2R,3R)-2-Hydroxy-3-methylpentanoate; L-*three*-3-Methyl-2-hydroxypentanoic acid (enantiomer); 2-Hydroxy-3-methylpentanoic acid (stereoisomer)
EINECS	Contact for details

Quality Control

Our (2R,3R)-2-Hydroxy-3-Methylpentanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.