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1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 86388-25-2


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CAS No.:86388-25-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class. This compound is a critical building block for constructing advanced lipid-based delivery systems and biomimetic membranes due to its defined, saturated fatty acid chains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise and reliable lipid components for liposomal drug delivery, vaccine adjuvants, and membrane biophysics studies.

Application

  • Liposomal Drug Formulation: A key excipient for creating stable, long-circulating liposomes for targeted delivery of chemotherapeutic agents, nucleic acids (siRNA, mRNA), and other therapeutic payloads.
  • Vaccine Adjuvant Development: Used in the research and production of lipid nanoparticle (LNP) systems and other vesicular adjuvants to enhance immune response.
  • Biomimetic Membrane Models: Serves as a fundamental component in creating synthetic bilayers and vesicles for studying membrane protein function, permeability, and cell signaling mechanisms.
  • Diagnostic Reagents: Incorporated into lipid-based assays and sensors for clinical diagnostics and research applications.
  • Cosmetic & Dermal Delivery Systems: Employed in the formulation of high-end cosmetic products and transdermal delivery systems for its membrane-mimicking and encapsulation properties.
  • Biophysical & Biochemical Research: A standard reagent for investigating lipid-lipid and lipid-protein interactions, membrane fusion, and phase behavior.

Basic Information

Product Name 1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No. 86388-25-2
Molecular Formula C₄₀H₈₀NO₈P
Molecular Weight 734.04 g/mol
Synonyms 1,2-Diheptadecanoyl-sn-glycero-3-phosphoethanolamine; PE(17:0/17:0); Diphytanoyl Phosphatidylethanolamine (common name for branched-chain analog, often used in searches); 1,2-Diheptadecanoylphosphatidylethanolamine; DHEPE; C17:0 PE; Phosphatidylethanolamine (C17:0); 3-sn-Phosphatidylethanolamine, 1,2-diheptadecanoyl-
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Quality Control

Our 1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and life science research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Solubility Soluble in chloroform, methanol, ethanol; insoluble in water
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 10 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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