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Ganciclovir Dipropionate CAS NO 86357-20-2


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CAS No.:86357-20-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ganciclovir Dipropionate is a prodrug ester derivative of the potent antiviral nucleoside analogue ganciclovir. This chemical modification is designed to enhance the bioavailability and pharmacokinetic profile of the parent compound, making it a critical intermediate in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of next-generation antiviral therapies, particularly for the treatment of cytomegalovirus (CMV) and other herpesvirus infections.

Application

  • Pharmaceutical Intermediate: Key synthetic precursor in the production of enhanced ganciclovir prodrug formulations.
  • Antiviral Drug Research: Used in R&D for developing novel antiviral agents with improved absorption and tissue distribution.
  • Biochemical Studies: Serves as a reference standard and tool compound in virology and pharmacology research.
  • Process Development: Employed in scaling up and optimizing manufacturing processes for antiviral active pharmaceutical ingredients (APIs).
  • Controlled-Release Formulations: Investigated for use in creating sustained-release drug delivery systems.

Basic Information

Product Name Ganciclovir Dipropionate
CAS No. 86357-20-2
Molecular Formula C16H23N5O6
Molecular Weight 381.39 g/mol
Synonyms 9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine dipropionate; Ganciclovir bis(propionate); Ganciclovir Dipropanoate; 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one dipropionate; GCV Dipropionate; DHPG Dipropionate; BN 52021 (Dipropionate Ester); NSC 710615
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Quality Control

Our Ganciclovir Dipropionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting purity (typically by HPLC), related substances, residual solvents, and other critical parameters are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥98.0%
Related Substances (HPLC) Total impurities ≤2.0%
Water Content (KF) ≤1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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