Description

Buciclovir CAS NO 86304-28-1 is a synthetic nucleoside analogue with significant antiviral activity. This compound is a key intermediate in the research and development of novel antiviral therapeutics, particularly those targeting herpesviruses. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antiviral drug candidates.
• Antiviral Research: Used in biochemical and virological studies to investigate mechanisms of action against DNA viruses.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Preclinical Development: Utilized in the formulation of compounds for in vitro and in vivo efficacy and toxicity studies.
• Academic Research: Supports university and institutional research into nucleoside chemistry and antiviral discovery.

Basic Information

Product Name	Buciclovir
CAS No.	86304-28-1
Molecular Formula	C8H11N5O3
Molecular Weight	225.21 g/mol
Synonyms	9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine; DHBG; 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one; 1,3-Dihydroxy-2-propoxymethylguanine; NSC 626466; BUCICLOVIR; BWB 759U
EINECS	Contact for details

Quality Control

Our Buciclovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.