Description

15(S)-Hepe CAS NO 86282-92-0 is a specialized, high-purity eicosapentaenoic acid (EPA) derivative, specifically the 15(S)-hydroperoxy form, which serves as a key bioactive lipid mediator and biosynthetic intermediate. This compound is of significant interest for its role in specialized pro-resolving mediator (SPM) pathways, offering critical research and development value in modulating inflammatory responses. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and advanced nutraceutical sectors for drug discovery, biochemical studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of lipoxygenase pathways, eicosanoid biosynthesis, and inflammation resolution mechanisms.
• Pharmaceutical R&D: Serves as a critical intermediate in the synthesis and development of novel anti-inflammatory and pro-resolving drug candidates.
• Cell Signaling Studies: Employed to investigate the role of oxylipins and lipid mediators in cellular communication and immune system regulation.
• Analytical Standard: Essential for the development and validation of analytical methods (HPLC, LC-MS) for quantifying lipid mediators in complex biological matrices.
• Nutraceutical Development: Investigated for potential applications in advanced nutritional supplements targeting metabolic and inflammatory health.
• Academic Research: A key tool for universities and research institutes exploring lipidomics, metabolomics, and molecular pharmacology.

Basic Information

Product Name	15(S)-Hepe
CAS No.	86282-92-0
Molecular Formula	C20H30O4
Molecular Weight	334.45 g/mol
Synonyms	15(S)-HpEPE; (5Z,8Z,11Z,13E,15S)-15-Hydroperoxyicosa-5,8,11,13-tetraenoic Acid; 15(S)-HPETE; 15S-Hydroperoxyeicosapentaenoic Acid; 15(S)-HpEPE; 15S-HpEPE; 15-Hydroperoxyeicosapentaenoic Acid (15S-isomer)
EINECS	Contact for details

Quality Control

Our 15(S)-Hepe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isomeric Purity (S-configuration)	≥ 98%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.