Description

Tertiary-Butyloxycarbonyl-Alanine Imidazolide CAS NO 86194-94-7 is a specialized, highly reactive amino acid derivative used as a key building block in peptide synthesis. Its primary value lies in its role as an activated ester, facilitating efficient and selective amide bond formation under mild conditions, which is critical for constructing complex biomolecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in the development of peptide-based therapeutics, diagnostic agents, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the efficient coupling of Boc-Alanine to growing peptide chains on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical solution methods for the preparation of short peptides and peptide fragments.
• Pharmaceutical Intermediate: Serves as a key building block in the research and production of active pharmaceutical ingredients (APIs) with alanine motifs.
• Bioconjugation: Employed to attach peptide sequences or alanine derivatives to other molecules like proteins, polymers, or surfaces for drug delivery systems and diagnostic probes.
• Combinatorial Chemistry: Utilized in library synthesis for high-throughput screening of novel bioactive compounds.
• Academic & Industrial Research: A fundamental tool for chemists studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Tertiary-Butyloxycarbonyl-Alanine Imidazolide
CAS No.	86194-94-7
Molecular Formula	C11H17N3O3
Molecular Weight	239.27 g/mol
Synonyms	Boc-Ala-Imidazolide; Boc-L-Alanine Imidazolide; N-(tert-Butoxycarbonyl)-L-alanine Imidazolide; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]propanoic acid Imidazolide; N-Boc-L-alanine Imidazolide; tert-Butyloxycarbonylalanine Imidazolide; Boc-Alanine Imidazolide; N-(tert-Butoxycarbonyl)alanine Imidazolide
EINECS	Contact for details

Quality Control

Our Tertiary-Butyloxycarbonyl-Alanine Imidazolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.