Description

trans-2-[[[1-(2-Aminothiazol-4-Yl)-2-[(2-Methyl-4-Oxo-1-Sulphoazetidin-3-Yl)Amino]-2-Oxoethylidene]Amino]Oxy]-2-Methylpropionic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex β-lactam structure. This compound is critical for the synthesis of next-generation cephalosporin antibiotics, offering a key building block for creating molecules with enhanced antibacterial activity and spectrum. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers focused on developing novel anti-infective therapies.

Application

• Key Intermediate in Cephalosporin Synthesis: Serves as a crucial precursor in the manufacturing of advanced third and fourth-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial agents with improved efficacy against resistant strains.
• Active Pharmaceutical Ingredient (API) Production: Integrated into the final chemical synthesis steps for producing bulk antibiotic APIs.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production from laboratory to commercial batch sizes.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing of finished antibiotic products.

Basic Information

Product Name	trans-2-[[[1-(2-Aminothiazol-4-Yl)-2-[(2-Methyl-4-Oxo-1-Sulphoazetidin-3-Yl)Amino]-2-Oxoethylidene]Amino]Oxy]-2-Methylpropionic Acid
CAS No.	85506-30-5
Molecular Formula	C13H17N5O8S2
Molecular Weight	435.43 g/mol
Synonyms	(2-Aminothiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid; 7β-[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-3-cephem-4-carboxylic acid side chain intermediate; Cephalosporin C-7 side chain acid; ATMA derivative; (Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetic acid linked β-lactam intermediate
EINECS	Contact for details

Quality Control

Our trans-2-[[[1-(2-Aminothiazol-4-Yl)-2-[(2-Methyl-4-Oxo-1-Sulphoazetidin-3-Yl)Amino]-2-Oxoethylidene]Amino]Oxy]-2-Methylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.