Description

1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine [R-(R*,R*)]-Tartrate is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. Its complex polycyclic structure makes it a valuable intermediate or active pharmaceutical ingredient (API) for synthesizing novel therapeutic agents. This compound is primarily utilized by pharmaceutical companies and research institutions focused on central nervous system (CNS) drugs, receptor modulators, and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research for potential APIs targeting specific neurological receptors and pathways.
• Medicinal Chemistry Research: A key compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions and enzyme inhibition related to its structural class.
• Preclinical Studies: Supplied for pharmacological and toxicological evaluation in the early stages of drug development.

Basic Information

Product Name	1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine [R-(R*,R*)]-Tartrate
CAS No.	85391-78-2
Molecular Formula	C23H26N2O6
Molecular Weight	426.47 g/mol
Synonyms	(R,R)-Mirtazapine Tartrate; (R,R)-Mirtazapine L-Tartrate; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine (R,R)-tartrate; Org 3770 (R,R)-tartrate; 6-Azamianserin (R,R)-tartrate; Remeron (R,R)-enantiomer tartrate salt; (14bR)-2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine (2R,3R)-2,3-dihydroxybutanedioate
EINECS	Contact for details

Quality Control

Our 1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine [R-(R*,R*)]-Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or nitrogen-purged environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (Chiral HPLC)	≥99.0% (R,R)-enantiomer
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.