Description

2-Bromo-4-Carboxy-Alpha,Alpha,α-Trifluoroanisole is a high-purity, multi-functional aromatic building block characterized by its bromine, carboxylic acid, and trifluoromethoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethoxy and halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the unique halogenated structure enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Employed as a monomer or modifying agent to create specialty polymers with enhanced thermal stability and chemical resistance.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A versatile building block in academic and industrial labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	2-Bromo-4-Carboxy-Alpha,Alpha,α-Trifluoroanisole
CAS No.	85373-96-2
Molecular Formula	C9H4BrF3O3
Molecular Weight	297.03 g/mol
Synonyms	2-Bromo-4-(trifluoromethoxy)benzoic Acid; 4-Carboxy-2-Bromo-α,α,α-Trifluoroanisole; 2-Bromo-α,α,α-trifluoro-p-anisic Acid; Benzoic acid, 2-bromo-4-(trifluoromethoxy)-; 2-Bromo-4-trifluoromethoxybenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Carboxy-Alpha,Alpha,α-Trifluoroanisole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.