Description

Citalopram Hydrochloride CAS NO 85118-27-0 is the hydrochloride salt of citalopram, a selective serotonin reuptake inhibitor (SSRI). This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy, safety, and batch-to-batch consistency of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant medications.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antidepressant tablets, capsules, and oral solutions.
• Generic Drug Production: Serves as the core component for generic versions of SSRI-based medications following patent expiry.
• Clinical Research: Used in preclinical and clinical studies for investigating new therapeutic applications or formulations.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, UV, and other assay methods.
• Formulation Development: Utilized in R&D for developing new dosage forms, including controlled-release or combination therapies.

Basic Information

Product Name	Citalopram Hydrochloride
CAS No.	85118-27-0
Molecular Formula	C20H22FN3O • HCl
Molecular Weight	405.87 g/mol
Synonyms	1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrochloride; (±)-Citalopram Hydrochloride; Citalopram HCl; Cipramil (trade name); Celexa (trade name); Citolapram Hydrochloride; Seropram (trade name); Nitalapram Hydrochloride
EINECS	Contact for details

Quality Control

Our Citalopram Hydrochloride is manufactured under strict quality management systems. It is tested to meet or exceed relevant pharmacopeial standards such as USP and EP. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.1% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.