Description

3,5-Bis(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its two electron-withdrawing trifluoromethyl groups. This structural motif is critical for modulating the lipophilicity, metabolic stability, and binding affinity of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including kinase inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the CF3 groups enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in catalysis and as a building block for functional materials.
• Organic Electronics Research: Employed in the synthesis of fluorinated molecular components for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic and binding studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a bifunctional, fluorinated phenylacetic acid moiety.

Basic Information

Item	Details
Product Name	3,5-Bis(Trifluoromethyl)Phenylacetic Acid
CAS No.	85068-33-3
Molecular Formula	C10H6F6O2
Molecular Weight	272.15 g/mol
Synonyms	[3,5-Bis(trifluoromethyl)phenyl]acetic Acid; 2-[3,5-Bis(trifluoromethyl)phenyl]acetic Acid; α-(3,5-Bis(trifluoromethyl)phenyl)acetic Acid; 3,5-Bis(trifluoromethyl)benzeneacetic Acid; 3,5-Di(trifluoromethyl)phenylacetic Acid; 3,5-Bis(trifluoromethyl)benzenacetic Acid; (3,5-Bis(trifluoromethyl)phenyl)ethanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3,5-Bis(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.