Description

Spergualin-15-Phosphate is a chemically modified derivative of the natural product spergualin, specifically phosphorylated at the 15-position. This modification is critical for enhancing the compound's stability and biological activity profile, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector focused on immunology and oncology, where precise chemical tools are essential for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel immunosuppressive and anti-cancer agents.
• Biochemical Research: Used as a reference standard or active compound in studies investigating cellular apoptosis and immune response modulation.
• Immunology Studies: Applied in preclinical research to explore mechanisms of action related to T-cell and B-cell function.
• Antitumor Agent Development: Investigated for its potential in creating new chemotherapeutic compounds due to its mechanism of inhibiting DNA synthesis.
• Enzyme Inhibition Studies: Utilized in enzymatic assays to study its effects on specific molecular targets within signal transduction pathways.

Basic Information

Product Name	Spergualin-15-Phosphate
CAS No.	84937-49-5
Molecular Formula	C17H37N7O6P
Molecular Weight	466.49 g/mol
Synonyms	15-Deoxyspergualin 15-Phosphate; 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione 15-Phosphate; (-)-15-Deoxyspergualin 15-Phosphate; DSG-15-Phosphate; Gusperimus 15-Phosphate; Spergualin Trihydrochloride Phosphate Derivative; 1,19-Bis(guanyl)-11-hydroxy-4,9,12-triazanonadecane-10,13-dione 15-Phosphate
EINECS	Contact for details

Quality Control

Our Spergualin-15-Phosphate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) guidelines for pharmaceutical intermediates, and specifications can be aligned with client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.