Description

Darenzepine is a selective muscarinic M1 receptor antagonist of significant interest in pharmacological research. This compound matters as a key tool for studying cholinergic pathways and receptor subtypes in the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in neuroscience, drug discovery, and the development of treatments for cognitive disorders.

Application

• Neuroscience Research: A critical pharmacological tool for investigating the role of muscarinic M1 receptors in learning, memory, and cognitive function.
• Drug Discovery & Development: Used in preclinical studies to validate targets and screen potential therapeutic compounds for neurological and psychiatric conditions.
• Biochemical Assays: Employed in receptor binding studies and functional assays to determine antagonist potency and selectivity.
• Academic Research: Supports fundamental studies in neuropharmacology and signal transduction mechanisms within academic laboratories.

Basic Information

Product Name	Darenzepine
CAS No.	84629-61-8
Molecular Formula	C20H21N3O2
Molecular Weight	335.40 g/mol
Synonyms	Darenzepine; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one; AF-DX 116; AFDX 116; AFDX-116; (5,11-Dihydro-6-oxo-6H-pyrido[2,3-b][1,4]benzodiazepin-11-yl)-1-[2-[(diethylamino)methyl]-1-piperidinyl]ethanone
EINECS	Contact for details

Quality Control

Our Darenzepine is produced under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.