Description

2'-o-Glycyl Acyclovir is a chemically modified prodrug derivative of the established antiviral agent acyclovir. This molecular modification is designed to enhance bioavailability and target specificity, offering a sophisticated tool for advanced pharmaceutical research and development. It is primarily utilized by research scientists and development teams in the pharmaceutical and biotechnology sectors working on next-generation antiviral therapies and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel antiviral prodrugs.
• Antiviral Research: Used in biochemical and pharmacological studies to investigate improved delivery mechanisms for acyclovir and related nucleoside analogues.
• Prodrug Development: A model compound for studying amino acid ester prodrug strategies aimed at enhancing membrane permeability and oral absorption.
• Targeted Therapy Exploration: Supports research into ligand-conjugated antiviral agents for more specific cellular targeting.
• Analytical Reference Standard: Employed as a high-purity standard in quality control (QC) and analytical method development for related pharmaceutical compounds.

Basic Information

Product Name	2'-o-Glycyl Acyclovir
CAS No.	84499-62-7
Molecular Formula	C12H18N6O5
Molecular Weight	326.31 g/mol
Synonyms	2'-O-Glycylacyclovir; Acyclovir 2'-O-glycinate; 9-[(2-Hydroxyethoxy)methyl]-2-amino-1,9-dihydro-6H-purin-6-one 2'-(glycyl ester); Glycine, 2-[[9-[(2-hydroxyethoxy)methyl]-6-oxo-1,6-dihydro-9H-purin-2-yl]amino]-, ethyl ester; Acyclovir glycinate ester; 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one 2'-O-(N-glycyl) derivative
EINECS	Contact for details

Quality Control

Our 2'-o-Glycyl Acyclovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.