Description

Tris(2-Fluorophenyl)Phosphane is a specialized organophosphorus compound featuring three ortho-fluorinated phenyl groups, which significantly influence its electronic and steric properties. This structural motif makes it a highly valuable ligand in transition metal catalysis, particularly for cross-coupling reactions where electron-deficient phosphines are advantageous. It is primarily sought after by pharmaceutical intermediates manufacturers and advanced materials researchers for developing novel synthetic pathways and functional polymers.

Application

• Pharmaceutical Synthesis: As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for constructing complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides through catalytic processes that require electron-poor phosphine ligands.
• Material Science: Employed in the synthesis of specialized polymers, OLED materials, and other electronic chemicals where fluorine substitution is critical for performance.
• Academic & Industrial R&D: Serves as a building block and catalyst component in exploratory chemistry for new reaction methodologies.
• Fine Chemical Production: Facilitates the synthesis of fluorinated aromatic compounds and other high-value specialty chemicals.

Basic Information

Product Name	Tris(2-Fluorophenyl)Phosphane
CAS No.	84350-73-2
Molecular Formula	C18H12F3P
Molecular Weight	316.26 g/mol
Synonyms	Tris(2-fluorophenyl)phosphine; Tri(2-fluorophenyl)phosphane; P(2-FC6H4)3; Tris(o-fluorophenyl)phosphine; Phosphorous tri(2-fluorophenyl) ester; 2-Fluorophenylphosphine, tris-; Tris(2-fluorophenyl)phosphate (common misnomer); Ligand for cross-coupling
EINECS	Contact for details

Quality Control

Our Tris(2-Fluorophenyl)Phosphane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.