Description

4-Acetoxy-2,3,5,6-Tetrafluorobenzoic Acid is a high-value fluorinated aromatic building block characterized by its benzoic acid core with acetoxy and tetrafluoro substitutions. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine pattern imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, particularly in the development of fluorine-containing APIs where the acetoxy group serves as a versatile handle for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atoms to improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies, contributing to improved dielectric anisotropy and stability.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers, including high-performance resins and coatings with enhanced chemical and thermal resistance.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex fluorinated aromatic structures via reactions at the carboxylic acid or acetoxy functional groups.

Basic Information

Product Name	4-Acetoxy-2,3,5,6-Tetrafluorobenzoic Acid
CAS No.	83789-90-6
Molecular Formula	C9H4F4O4
Molecular Weight	252.12 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-acetoxybenzoic Acid; 4-(Acetyloxy)-2,3,5,6-tetrafluorobenzoic Acid; Benzoic acid, 4-(acetyloxy)-2,3,5,6-tetrafluoro-; Perfluoro-4-acetoxybenzoic Acid; Tetrafluoro-4-acetoxybenzoic Acid; 4-Acetoxytetrafluorobenzoic Acid; Acetic acid 2,3,5,6-tetrafluoro-4-carboxyphenyl ester
EINECS	Contact for details

Quality Control

Our 4-Acetoxy-2,3,5,6-Tetrafluorobenzoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.