Description

15(R)-Hete is a specific stereoisomer of the hydroxyeicosatetraenoic acid family, a class of bioactive lipid mediators derived from arachidonic acid. This compound matters for its role as a potent and selective ligand for the BLT2 receptor, making it a critical tool for research in inflammation, immune response, and related signaling pathways. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutics for inflammatory diseases, asthma, and cancer.

Application

• Biochemical Research: As a high-purity reference standard for analytical method development and validation in lipidomics studies.
• Pharmacology Studies: Used to investigate the role of the BLT2 receptor in various disease models, including inflammatory and autoimmune disorders.
• Drug Discovery & Development: Serves as a key intermediate or biological probe in screening assays and target validation for novel anti-inflammatory drugs.
• Cell Signaling Research: Employed to study eicosanoid-mediated signaling cascades and their effects on cell proliferation, migration, and apoptosis.
• Academic Research: Essential for university and institutional labs conducting fundamental research on lipid mediators and their physiological functions.

Basic Information

Product Name	15(R)-Hete
CAS No.	83603-31-0
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	15(R)-HETE; 15(R)-Hydroxyeicosatetraenoic acid; (15R)-HETE; 15R-HETE; 15R-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid; 15(R)-HETE-d8 (deuterated analog); BLT2 receptor ligand; 15R-Hydroxyarachidonic acid
EINECS	Contact for details

Quality Control

Our 15(R)-Hete is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be provided to meet the stringent requirements of pharmaceutical R&D and analytical laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, solutions are recommended to be prepared in anhydrous ethanol or other suitable organic solvents and kept at -80°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98% (by NMR)
Stereochemical Purity	≥ 99% 15(R) enantiomer (by Chiral HPLC)
Solubility	Soluble in ethanol, DMSO, DMF; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.