Description

Dihydrocyclosporinh is a derivative of the well-known immunosuppressive agent cyclosporine, identified by CAS NO 83602-88-4. This compound is of significant interest in pharmaceutical research and development for its potential to modulate biological activity with an altered pharmacological profile. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector, particularly those focused on immunology, drug discovery, and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cyclosporine analogs and related therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies investigating immunosuppressive pathways, structure-activity relationships (SAR), and enzyme inhibition.
• Process Development: Employed in the development and optimization of synthetic routes for complex macrocyclic compounds within R&D and pilot-scale production.
• Analytical Standard: Utilized for method development, calibration, and quality control in analytical laboratories using techniques like HPLC and LC-MS.
• Drug Discovery: Acts as a starting material or precursor for creating targeted libraries of compounds for high-throughput screening against various biological targets.

Basic Information

Product Name	Dihydrocyclosporinh
CAS No.	83602-88-4
Molecular Formula	C62H111N11O12
Molecular Weight	1202.6 g/mol
Synonyms	Dihydro-Cyclosporin H; [Dihydro]Cyclosporin H; Cyclosporin H Dihydro Derivative; [Dihydro]-CsH; CsH Dihydro Form; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,3S,4R)-3-hydroxy-2-methyl-4-(methylamino)-1-(2-methylpropyl)cyclohexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazatricyclo[30.3.0.012,16]pentatriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
EINECS	Contact for details

Quality Control

Our Dihydrocyclosporinh is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.