Description

Diisopropyl (R)-(+)-Malate is a high-purity chiral ester derivative of malic acid, specifically the (R)-(+)-enantiomer. This compound is a valuable chiral building block and resolving agent in asymmetric synthesis, prized for its defined stereochemistry and reactivity. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereocontrol is critical for developing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent to induce stereoselectivity in organic reactions.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific optical activity.
• Agrochemical Research: Serves as a precursor in developing chiral pesticides and herbicides with enhanced efficacy.
• Catalyst and Ligand Preparation: A starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric transformations.
• Academic and R&D Laboratories: A standard reagent for methodological development in synthetic organic and medicinal chemistry.

Basic Information

Product Name	Diisopropyl (R)-(+)-Malate
CAS No.	83540-97-0
Molecular Formula	C10H18O5
Molecular Weight	218.25 g/mol
Synonyms	(R)-(+)-Diisopropyl Malate; (R)-Diisopropyl 2-Hydroxysuccinate; (R)-(+)-Hydroxysuccinic Acid Diisopropyl Ester; (R)-Malic Acid Diisopropyl Ester; DIPRM; Bis(1-methylethyl) (2R)-2-hydroxybutanedioate; (R)-1,4-Diisopropyl 2-hydroxybutanedioate
EINECS	Contact for details

Quality Control

Our Diisopropyl (R)-(+)-Malate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.