Description

2-Amino-5-Trifluoromethyl-Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a trifluoromethyl-substituted benzene ring, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require specific fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-5-Trifluoromethyl-Benzoic Acid
CAS No.	83265-53-6
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-(Trifluoromethyl)anthranilic Acid; 2-Amino-α,α,α-trifluoro-p-toluic Acid; Benzoic acid, 2-amino-5-(trifluoromethyl)-; 2-Amino-5-trifluoromethylbenzoic acid; 5-Trifluoromethylanthranilic Acid; 2-Carboxy-4-trifluoromethylaniline; 4-Trifluoromethyl-2-aminobenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Trifluoromethyl-Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.