Description

(4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-Trihydroxydocosa-4,8,10,12,14,19-Hexaenoic Acid is a specialized, highly unsaturated fatty acid derivative with a complex stereochemistry that underpins its potent biological activity. This compound matters for its role as a key intermediate or reference standard in advanced pharmaceutical research and the development of bioactive lipid mediators. It is primarily needed by research institutions and pharmaceutical companies focused on inflammation, immunology, and metabolic pathways, where precise molecular structure is critical for efficacy.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard or intermediate in the synthesis of specialized pro-resolving mediators (SPMs) for studying inflammatory resolution.
• Biochemical Research: Used as a high-purity substrate or ligand in enzymatic studies and receptor binding assays to investigate lipid signaling pathways.
• Analytical Standard: Employed as a certified reference material (CRM) for the accurate quantification and identification of related lipid metabolites in complex biological samples via LC-MS or HPLC.
• Drug Discovery: Acts as a lead compound or a building block for the development of novel therapeutics targeting chronic inflammatory diseases, cardiovascular conditions, and metabolic disorders.
• Academic Research: Utilized in university and institutional labs for fundamental studies on the biosynthesis and biological functions of oxylipins and polyunsaturated fatty acid derivatives.

Basic Information

Product Name	(4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-Trihydroxydocosa-4,8,10,12,14,19-Hexaenoic Acid
CAS No.	82864-77-5
Molecular Formula	C22H34O5
Molecular Weight	378.50 g/mol
Synonyms	7,16,17-TriHDHA; 7(R),16,17(S)-Trihydroxydocosa-4Z,8E,10Z,12E,14E,19Z-hexaenoic acid; Resolvin D5; RvD5; (4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-Trihydroxy-4,8,10,12,14,19-docosahexaenoic Acid; 7,16,17-Trihydroxydocosahexaenoic Acid; Lipid Mediator RvD5; Specialized Pro-resolving Mediator
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques including HPLC, LC-MS, and NMR to confirm identity, stereochemical purity, and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with every shipment to ensure traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC, Area %)	≥ 95.0%
Assay (by HPLC)	≥ 90.0%
Stereochemical Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.