Description

L-Lysine Hydrochloride-15N is a stable isotope-labeled derivative of the essential amino acid L-Lysine, where the nitrogen atoms are enriched with the 15N isotope. This compound is a critical tool for advanced research and analytical applications, providing a non-radioactive tracer for metabolic and proteomic studies. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in mass spectrometry, NMR spectroscopy, and nutritional research.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies to investigate protein synthesis, turnover, and amino acid metabolism in biological systems.
• Proteomics & Quantitative Mass Spectrometry: Serves as an internal standard for the accurate quantification of lysine and lysine-containing peptides in SILAC (Stable Isotope Labeling by Amino acids in Cell culture) and other quantitative proteomic workflows.
• Nutritional & Biomedical Research: Employed in studies of human and animal nutrition to trace the incorporation of amino acids into tissues and assess protein utilization and requirements.
• Pharmaceutical Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules containing lysine moieties or to label therapeutic proteins.
• Environmental & Agricultural Science: Applied in research on nitrogen cycling in soil and plants, utilizing the 15N label to trace nutrient uptake and assimilation.

Basic Information

Item	Detail
Product Name	L-Lysine Hydrochloride-15N
CAS No.	82783-00-4
Molecular Formula	C₆H₁₅ClN₂O₂ *xH₂O (x=0-1)
Molecular Weight	182.65 g/mol (anhydrous)
Synonyms	(2S)-2,6-Diaminohexanoic acid hydrochloride-15N; Lysine-15N hydrochloride; L-Lysine-15N HCl; L-Lysine monohydrochloride-15N; H-Lys-OH•HCl-15N; (S)-2,6-Diaminocaproic acid hydrochloride-15N; 15N-L-Lysine•HCl
EINECS	Contact for details

Quality Control

Our L-Lysine Hydrochloride-15N is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including isotopic enrichment analysis by NMR or MS, chiral purity verification, and chemical purity assessment by HPLC. Certificates of Analysis (COA) detailing isotopic purity (atom % 15N), chemical purity, and specific tests are provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent absorption of water, which can affect stability and analytical performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 15N)	≥ 98%
Chemical Purity (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰/D: +20.5° to +21.5° (c=2 in 6N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.