Description

L-Methionine (15N) is a stable isotope-labeled form of the essential sulfur-containing amino acid, L-Methionine, where the nitrogen atom is enriched with the 15N isotope. This labeled compound is a critical tool for advanced research, enabling precise metabolic pathway tracing, protein turnover studies, and quantitative proteomics using mass spectrometry. It is indispensable for scientists and manufacturers in pharmaceutical research, nutritional science, and agricultural biochemistry who require high-fidelity isotopic tracers for their analytical and developmental work.

Application

• Metabolic Research & Tracer Studies: Used as a stable isotopic tracer to investigate amino acid metabolism, protein synthesis rates, and metabolic fluxes in biological systems.
• Quantitative Proteomics & Mass Spectrometry: Serves as an internal standard for the accurate quantification of proteins and peptides in complex biological samples via techniques like SILAC (Stable Isotope Labeling by Amino acids in Cell culture).
• Pharmaceutical Development: Employed in the research and development of new drugs, particularly in studying drug-amino acid interactions and bioavailability.
• Nutritional Science: Used in studies to understand methionine utilization, requirements, and its role in human and animal nutrition.
• Agricultural & Animal Feed Research: Applied in research to optimize feed formulations and study nitrogen metabolism in livestock.
• NMR Spectroscopy: The 15N label provides a sensitive probe for nuclear magnetic resonance (NMR) studies of protein structure, dynamics, and interactions.

Basic Information

Product Name	L-Methionine (15N)
CAS No.	82572-25-6
Molecular Formula	C5H1115NO2S
Molecular Weight	150.21 g/mol (for 15N labeled form)
Synonyms	(S)-2-Amino-4-(methylthio)butyric acid-15N; L-2-Amino-4-(methylthio)butyric acid-15N; (S)-2-Amino-4-(methylmercapto)butyric acid-15N; 15N-L-Methionine; L-Methionine-15N; Methionine-15N; 15N Labeled L-Methionine; Stable Isotope Labeled L-Methionine
EINECS	Contact for details

Quality Control

Our L-Methionine (15N) is produced and tested under stringent conditions to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 15N), chemical purity, chiral purity, and residual solvent content. We adhere to rigorous in-house quality standards to guarantee batch-to-batch consistency and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 15N)	≥ 98%
Assay (HPLC)	≥ 98.0%
Chiral Purity ([α]D / HPLC)	≥ 99.0% L-Isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.