Description

1-[4-(2-Dimethylaminoethoxy)[14C]Phenyl)]-1,2-Diphenylbutan-1-Ol CAS NO 82407-94-1 is a radiolabeled compound, specifically a carbon-14 ([14C]) isotopologue of a substituted butanol derivative. This product is of critical importance for pharmaceutical research and development, serving as a vital tracer in drug metabolism and pharmacokinetic (DMPK) studies. It is primarily needed by research scientists and analytical laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors for conducting advanced ADME (Absorption, Distribution, Metabolism, and Excretion) research.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to elucidate the metabolic fate and biotransformation pathways of pharmaceutical compounds in in vitro and in vivo studies.
• Mass Balance Studies: Essential for conducting quantitative mass balance studies to track the total recovery of a drug and its metabolites.
• Autoradiography: Employed in whole-body autoradiography (QWBA) and micro-autoradiography studies to visualize the spatial distribution of a drug within tissues.
• Bioanalytical Method Development: Serves as a critical reference standard for developing and validating sensitive Liquid Chromatography-Mass Spectrometry (LC-MS) and radiochemical detection methods.
• Receptor Binding Assays: Can be utilized in radioligand binding assays to study drug-receptor interactions, depending on the parent compound's pharmacology.
• Environmental Fate Studies: Applied in environmental science to study the degradation and movement of chemical analogs in ecosystems.

Basic Information

Product Name	1-[4-(2-Dimethylaminoethoxy)[14C]Phenyl)]-1,2-Diphenylbutan-1-Ol
CAS No.	82407-94-1
Molecular Formula	C26H31NO2 ([14C] labeled)
Molecular Weight	~389.53 g/mol (exact mass depends on [14C] position)
Synonyms	[14C]-Labeled Tamoxifen Metabolite Derivative; 1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-[14C]butan-1-ol; [14C]-(Z)-4-Hydroxytamoxifen analog; Radiolabeled triphenylethylene derivative; Carbon-14 labeled substituted butanol; [14C]-DMEP-DPBO; [14C]-1-(4-(2-(Dimethylamino)ethoxy)phenyl)-1,2-diphenylbutan-1-ol
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is produced and analyzed under strict quality control protocols to ensure high radiochemical purity and specific activity. Our quality commitment includes verification of identity and purity by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing radiochemical purity (by HPLC with radiometric detection), specific activity, chemical purity, and solvent content. Production follows cGMP-aligned procedures suitable for research use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at or below -20°C. The product is sensitive to light (store away from light). Store in accordance with local regulations for radioactive materials. Allow the product to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (HPLC-MS)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Chemical Purity (HPLC)	≥ 95%
Solvent (if supplied as solution)	Ethanol or Toluene (Specified per batch)
Radioisotope	Carbon-14 ([14C])

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.