Description

Atomoxetine Hydrochloride is a selective norepinephrine reuptake inhibitor (NRI) used as the active pharmaceutical ingredient (API) in the treatment of attention deficit hyperactivity disorder (ADHD). This compound matters for its specific mechanism of action, offering a non-stimulant therapeutic option for patients. It is primarily needed by pharmaceutical manufacturers and research institutions engaged in the development and production of neuropsychiatric medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in non-stimulant ADHD medications.
• Clinical Research: Utilized in pharmacological studies and clinical trials for neuropsychiatric disorders.
• Formulation Development: Serves as a key component in the R&D of solid oral dosage forms like capsules and tablets.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control and method validation.
• Biochemical Research: Employed in studies investigating norepinephrine transporter (NET) function and related neurological pathways.

Basic Information

Product Name	Atomoxetine Hydrochloride
CAS No.	82248-59-7
Molecular Formula	C17H21NO • HCl
Molecular Weight	291.82 g/mol
Synonyms	Tomoxetine Hydrochloride; (R)-N-Methyl-3-phenyl-3-(o-tolyloxy)propylamine Hydrochloride; LY139603; (R)-Atomoxetine HCl; (-)-Atomoxetine Hydrochloride; (R)-Tomoxetine Hydrochloride; Strattera (Brand Name API)
EINECS	Contact for details

Quality Control

Our Atomoxetine Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with relevant pharmacopeial standards (e.g., USP, EP) and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Optical Rotation	-10.0° to -12.0° (c=1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.