Description

(3S)-3-[[(S)-2-Acetylamino-3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-2-Oxo-1-Azetidinesulfonic Acid is a specialized β-lactam sulfonic acid derivative of significant interest in advanced pharmaceutical research and synthesis. This compound serves as a critical chiral building block and intermediate for developing novel enzyme inhibitors and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel β-lactamase inhibitors and other therapeutic compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate serine protease mechanisms.
• Organic Synthesis: Serves as a versatile building block for constructing complex molecules with azetidinone and sulfonic acid functionalities.
• API Development: Intermediate in the synthetic pathway for potential new drugs targeting bacterial resistance.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	(3S)-3-[[(S)-2-Acetylamino-3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-2-Oxo-1-Azetidinesulfonic Acid
CAS No.	82144-71-6
Molecular Formula	C14H17N3O7S
Molecular Weight	371.37 g/mol
Synonyms	(3S)-3-[[(S)-2-Acetamido-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-2-oxo-1-azetidinesulfonic acid; 3-[(S)-2-Acetamido-3-(4-hydroxyphenyl)propanamido]-2-oxoazetidine-1-sulfonic acid; 1-Azetidinesulfonic acid, 3-[[(2S)-2-(acetylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-2-oxo-, (3S)-; β-Lactam sulfonic acid derivative; Azetidinone sulfonate intermediate
EINECS	Contact for details

Quality Control

Our (3S)-3-[[(S)-2-Acetylamino-3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-2-Oxo-1-Azetidinesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.