Description

(5R,6R)-3-[(2-Aminoethyl)Thio]-6-[(S)-1-Sulfooxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid CAS NO 81623-61-2 is a chemically synthesized, advanced pharmaceutical intermediate. This compound is of significant commercial importance due to its role as a key precursor in the synthesis of modern β-lactam antibiotics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of novel antibacterial agents.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A critical building block in the production of specific cephalosporin-class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial compounds with improved efficacy.
• Process Chemistry: Serves as a key intermediate in the scale-up and optimization of antibiotic manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of finished pharmaceutical products.
• Biochemical Studies: Utilized in research to study the mechanism of action and resistance profiles of β-lactam antibiotics.

Basic Information

Product Name	(5R,6R)-3-[(2-Aminoethyl)Thio]-6-[(S)-1-Sulfooxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	81623-61-2
Molecular Formula	C12H18N2O7S2
Molecular Weight	366.41 g/mol
Synonyms	6-(1-Sulfooxyethyl)-3-[(2-aminoethyl)thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6R)-3-[(2-Aminoethyl)thio]-6-[(1S)-1-(sulfooxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Cefotaxime Intermediate; Cefotaxime Sulfooxy Ester; 7-ACA Derivative; β-lactam Intermediate; Antibiotic Synthesis Intermediate
EINECS	Contact for details

Quality Control

Our (5R,6R)-3-[(2-Aminoethyl)Thio]-6-[(S)-1-Sulfooxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is manufactured under strict quality systems. We provide material that meets high-purity pharmaceutical intermediate standards, with specifications tailored to customer process requirements. Comprehensive testing, including identity, purity, and impurity profile analysis, is performed. Certificates of Analysis (COA) documenting all test results are available for each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. Due to its light-sensitive nature, handling should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.