Description

(R,R)-1,2-Bis[(2-Methylphenyl)(Phenyl)Phosphino]Ethane is a chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of optically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• Key component in rhodium- and ruthenium-catalyzed reactions for the synthesis of chiral pharmaceutical intermediates.
• Enabling technology for the production of optically active amino acids and their derivatives.
• Catalyst system for asymmetric isomerization and carbon-carbon bond-forming reactions.
• Critical for process chemistry in the scale-up of enantiomerically pure active pharmaceutical ingredients (APIs).
• Research and development of novel catalytic methodologies in academic and industrial laboratories.

Basic Information

Product Name	(R,R)-1,2-Bis[(2-Methylphenyl)(Phenyl)Phosphino]Ethane
CAS No.	81157-90-6
Molecular Formula	C30H30P2
Molecular Weight	452.50 g/mol
Synonyms	(R,R)-DIPAMP; (R,R)-1,2-Bis(o-anisylphenylphosphino)ethane (common misnomer); (R,R)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane (common misnomer); (R,R)-Bis[(2-methylphenyl)phenylphosphino]ethane; (R,R)-1,2-Bis[(2-tolyl)(phenyl)phosphino]ethane; (R,R)-Ethane-1,2-diylbis[(2-methylphenyl)phenylphosphane]; (R,R)-o-Tol-P-Phos
EINECS	Contact for details

Quality Control

Our (R,R)-1,2-Bis[(2-Methylphenyl)(Phenyl)Phosphino]Ethane is manufactured under strict quality systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, 31P NMR, and 1H NMR, to verify identity, enantiomeric excess, and chemical purity. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.