Description

Spergualin Trihydrochloride is a potent immunosuppressive agent and antitumor antibiotic derived from the bacterium *Bacillus laterosporus*. This compound is of significant interest in pharmaceutical research and development due to its unique mechanism of action, which involves the inhibition of polyamine biosynthesis and the induction of apoptosis in certain cell lines. It serves as a critical reference standard and active pharmaceutical ingredient (API) for researchers and manufacturers in the fields of immunology, oncology, and transplant medicine, facilitating the study of novel therapeutic pathways and drug formulations.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) in drug development and quality control laboratories.
• Immunosuppressive Research: A key tool compound for studying mechanisms of immune response modulation and developing therapies for autoimmune diseases and organ transplantation.
• Oncology Research: Investigated for its antitumor properties in preclinical studies targeting various cancer cell lines.
• Biochemical Research: Employed in studies of polyamine metabolism and its role in cell growth and differentiation.
• Active Pharmaceutical Ingredient (API): Serves as a starting material or intermediate in the synthesis of more complex therapeutic agents.

Basic Information

Product Name	Spergualin Trihydrochloride
CAS No.	80952-47-2
Molecular Formula	C17H37N7O4 • 3HCl
Molecular Weight	539.9 g/mol (as trihydrochloride salt)
Synonyms	15-Deoxyspergualin Trihydrochloride; (-)-15-Deoxyspergualin Trihydrochloride; 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione Trihydrochloride; Gusperimus Trihydrochloride; DSG Trihydrochloride; NSC-356894; Spanidin; Spergualin 3HCl
EINECS	Contact for details

Quality Control

Our Spergualin Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.