Description

Adenylyl-(3'-5')-Virazole is a chemically modified nucleotide analog, specifically an adenylyl derivative of the antiviral agent virazole (ribavirin). This compound is of significant interest in biochemical and pharmaceutical research for its potential to act as a chain terminator or inhibitor in RNA synthesis and viral replication studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug development, nucleotide chemistry, and enzymology. The product is supplied as a high-purity material suitable for laboratory and investigational use.

Application

• Antiviral Research: Used as a biochemical tool to study the mechanism of action of nucleotide analogs and their inhibition of viral polymerases.
• Nucleotide Chemistry: Serves as a specialized substrate or intermediate in the synthesis of novel nucleoside and nucleotide derivatives.
• Enzymology Studies: Employed to investigate the activity and specificity of enzymes such as RNA ligases, polymerases, and phosphodiesterases.
• Molecular Biology: Potential use in probing RNA structure and function, or as a chain-terminating agent in sequencing-related applications.
• Pharmaceutical Development: Acts as a reference standard or a lead compound in the discovery and development of new antiviral therapeutics.

Basic Information

Product Name	Adenylyl-(3'-5')-Virazole
CAS No.	80948-57-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3'-5'-Adenylylribavirin; Adenylylribavirin; Adenosine 3',5'-ribavirin phosphate; Ribavirin adenylyl (3'→5') ester; 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, 5'-ester with 5'-adenylic acid
EINECS	Contact for details

Quality Control

Our Adenylyl-(3'-5')-Virazole is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.