Description

Spergualin is a potent immunosuppressive and antitumor antibiotic compound originally isolated from *Bacillus laterosporus*. Its unique mechanism of action, involving the inhibition of polyamine biosynthesis and interference with nuclear factor kappa B (NF-κB) signaling, makes it a compound of significant research interest. This product is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the investigation of novel immunomodulatory therapies and anticancer agents.

Application

• Pharmaceutical Research: Key intermediate in the synthesis and development of novel immunosuppressive drugs.
• Oncology Studies: Investigated as a potential chemotherapeutic agent due to its antitumor properties.
• Immunology Research: Used as a tool compound to study immune response modulation and transplant rejection mechanisms.
• Biochemical Standard: Serves as a high-purity reference standard for analytical method development and quality control in API manufacturing.
• Preclinical Development: Employed in *in vitro* and *in vivo* studies to assess efficacy and pharmacokinetics of related analogues.

Basic Information

Product Name	Spergualin
CAS No.	80902-43-8
Molecular Formula	C17H37N7O4
Molecular Weight	403.53 g/mol
Synonyms	15-Deoxyspergualin; DSG; Gusperimus; 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione; (-)-15-Deoxyspergualin; (S)-(-)-15-Deoxyspergualin; NSC-356894; Spergualin trihydrochloride
EINECS	Contact for details

Quality Control

Our Spergualin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.