Description

Brivudine 5''-Monophosphate is a nucleotide analog monophosphate derivative, serving as a key pharmaceutical intermediate. Its primary value lies in its role as a prodrug for the antiviral agent Brivudine, enabling targeted therapeutic action. This high-purity compound is essential for research institutions and pharmaceutical manufacturers engaged in the development and production of antiviral medications, particularly those targeting herpesviruses.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of the antiviral drug Brivudine (Sorivudine).
• Antiviral Research: Used in biochemical and pharmacological studies to investigate nucleotide metabolism and antiviral mechanisms of action.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a building block in GMP-compliant production processes for final dosage forms.
• Virology Studies: Employed in laboratory settings to study the inhibition of viral DNA polymerase.
• Reference Standard: Utilized as a high-purity standard for analytical method development and quality control testing.

Basic Information

Product Name	Brivudine 5''-Monophosphate
CAS No.	80860-82-8
Molecular Formula	C15H19BrN2O9P
Molecular Weight	491.20 g/mol
Synonyms	5-[(2-Bromo-5-vinyl-1H-pyrrol-1-yl)methyl]-2'-deoxyuridine 5'-monophosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 5'-monophosphate; BVDU-MP; Brivudine Monophosphate; Sorivudine 5'-Monophosphate; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[(E)-2-bromovinyl]pyrimidine-2,4-dione 5'-(dihydrogen phosphate); BVdUMP
EINECS	Contact for details

Quality Control

Our Brivudine 5''-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent limits for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.