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R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid CAS NO 80703-23-7
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CAS No.:80703-23-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid is a high-purity, axially chiral dicarboxylic acid derivative, serving as a critical building block in asymmetric synthesis and advanced materials science. Its rigid, non-racemic binaphthyl backbone provides a versatile scaffold for constructing chiral ligands, catalysts, and functional polymers. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing active ingredients and high-performance materials.
Application
- Chiral Ligand & Catalyst Synthesis: A key precursor for preparing BINOL and BINAP-type ligands used in asymmetric hydrogenation, coupling, and addition reactions.
- Pharmaceutical Intermediates: Employed in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for various therapeutic areas.
- Advanced Material Monomers: Used to create chiral polymers, metal-organic frameworks (MOFs), and liquid crystals with specific optical and electronic properties.
- Agrochemical Development: Serves as a chiral synthon for producing novel, stereoselective herbicides, fungicides, and plant growth regulators.
- Analytical Chiral Stationary Phases: Functionalized onto silica gel or other supports to create HPLC columns for enantiomeric separation and analysis.
- Supramolecular Chemistry: Acts as a building block for designing chiral host molecules and molecular recognition systems.
Basic Information
| Product Name | R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid |
| CAS No. | 80703-23-7 |
| Molecular Formula | C22H14O4 |
| Molecular Weight | 342.34 g/mol |
| Synonyms | (R)-1,1'-Binaphthyl-2,2'-dicarboxylic Acid; (R)-BINOL-2,2'-dicarboxylic Acid; (R)-[1,1'-Binaphthalene]-2,2'-dicarboxylic Acid; (R)-2,2'-Dihydroxy-1,1'-binaphthyl-6,6'-dicarboxylic Acid (precursor form); (R)-BINAP Dicarboxylic Acid Derivative; (R)-1,1'-Bi-2-naphthoic Acid; (R)-BINOL Dicarboxylate |
| EINECS | Contact for details |
Quality Control
Our R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (ee), and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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