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R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid CAS NO 80703-23-7


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CAS No.:80703-23-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid is a high-purity, axially chiral dicarboxylic acid derivative, serving as a critical building block in asymmetric synthesis and advanced materials science. Its rigid, non-racemic binaphthyl backbone provides a versatile scaffold for constructing chiral ligands, catalysts, and functional polymers. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing active ingredients and high-performance materials.

Application

  • Chiral Ligand & Catalyst Synthesis: A key precursor for preparing BINOL and BINAP-type ligands used in asymmetric hydrogenation, coupling, and addition reactions.
  • Pharmaceutical Intermediates: Employed in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for various therapeutic areas.
  • Advanced Material Monomers: Used to create chiral polymers, metal-organic frameworks (MOFs), and liquid crystals with specific optical and electronic properties.
  • Agrochemical Development: Serves as a chiral synthon for producing novel, stereoselective herbicides, fungicides, and plant growth regulators.
  • Analytical Chiral Stationary Phases: Functionalized onto silica gel or other supports to create HPLC columns for enantiomeric separation and analysis.
  • Supramolecular Chemistry: Acts as a building block for designing chiral host molecules and molecular recognition systems.

Basic Information

Product Name R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid
CAS No. 80703-23-7
Molecular Formula C22H14O4
Molecular Weight 342.34 g/mol
Synonyms (R)-1,1'-Binaphthyl-2,2'-dicarboxylic Acid; (R)-BINOL-2,2'-dicarboxylic Acid; (R)-[1,1'-Binaphthalene]-2,2'-dicarboxylic Acid; (R)-2,2'-Dihydroxy-1,1'-binaphthyl-6,6'-dicarboxylic Acid (precursor form); (R)-BINAP Dicarboxylic Acid Derivative; (R)-1,1'-Bi-2-naphthoic Acid; (R)-BINOL Dicarboxylate
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Quality Control

Our R-1,1'-Binaphthyl-2,2'-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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