Description

23-Dehydro-25-Hydroxyvitamin D3 is a key intermediate metabolite in the vitamin D metabolic pathway, specifically related to the activation and regulation of calcitriol. This compound matters for researchers and manufacturers as it provides critical insights into vitamin D metabolism and serves as a vital building block for synthesizing more complex vitamin D analogs. It is primarily needed by the pharmaceutical, biotechnology, and life science research sectors for drug discovery, metabolic studies, and the development of therapeutic agents targeting bone health, immune function, and cellular regulation.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced vitamin D analogs and active pharmaceutical ingredients (APIs) for therapeutic use.
• Biochemical Research: Used as a reference standard and reagent in metabolic pathway studies to understand the activation and function of vitamin D.
• Drug Discovery & Development: Serves as a key molecular scaffold for creating new compounds targeting vitamin D receptors in various disease models.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry for the qualitative and quantitative analysis of vitamin D metabolites.
• Nutritional Science Research: Utilized in studies investigating the role of vitamin D metabolites in calcium homeostasis and bone health.

Basic Information

Product Name	23-Dehydro-25-Hydroxyvitamin D3
CAS No.	80463-19-0
Molecular Formula	C₂₇H₄₂O₂
Molecular Weight	398.63 g/mol
Synonyms	(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3β,25-diol; 25-Hydroxy-23-dehydrovitamin D3; 23-Dehydrocalcifediol; 25-Hydroxy-23-dehydrocholecalciferol; 23-Dehydro-25-OH-D3; 25-Hydroxyprovitamin D3 (23-dehydro); Vitamin D3 metabolite intermediate
EINECS	Contact for details

Quality Control

Our 23-Dehydro-25-Hydroxyvitamin D3 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under an inert atmosphere at lower temperatures (-20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.