Description

1,2,3-Thiadiazole-5-Carboxaldoxime Glucuronide is a specialized biochemical conjugate, representing a key metabolite or synthetic intermediate in advanced research and development. This compound is of significant interest for its role in metabolic studies and as a potential reference standard in analytical chemistry. It is primarily sought by researchers and developers in the pharmaceutical and agrochemical industries for applications in drug metabolism and pharmacokinetics (DMPK) studies, biomarker research, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant or control material in bioanalytical methods for quantifying drug metabolites.
• Drug Metabolism & Pharmacokinetics (DMPK): Critical for in vitro and in vivo studies to understand the metabolic pathways and clearance mechanisms of parent thiadiazole compounds.
• Biomarker Research: Serves as a definitive standard in the development of diagnostic assays for detecting specific metabolic signatures.
• Agrochemical Metabolite Analysis: Employed in environmental and regulatory science to study the fate and transformation of thiadiazole-based pesticides.
• Synthetic Intermediate: Used in the targeted synthesis of more complex glucuronidated molecules for biological evaluation.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, toxicology, and biochemical conjugation processes.

Basic Information

Product Name	1,2,3-Thiadiazole-5-Carboxaldoxime Glucuronide
CAS No.	80238-98-8
Molecular Formula	C10H12N4O8S
Molecular Weight	348.29 g/mol
Synonyms	5-(Hydroxyimino)methyl-1,2,3-thiadiazole β-D-glucopyranosiduronic acid; 1,2,3-Thiadiazole-5-carboxaldehyde oxime glucuronide; Thiadiazolecarboxaldoxime glucuronide; Glucuronic acid conjugate of 1,2,3-thiadiazole-5-carboxaldoxime; TDZ-COX-Gluc; (1,2,3-Thiadiazol-5-yl)-N-hydroxy-methanimine glucuronide; 5-Carboxaldoximido-1,2,3-thiadiazole glucuronide
EINECS	Contact for details

Quality Control

Our 1,2,3-Thiadiazole-5-Carboxaldoxime Glucuronide is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.