Description

D-Glucose-Ul-14C is a uniformly carbon-14 labeled isotopologue of D-glucose, a fundamental monosaccharide and primary energy source in biological systems. This radiolabeled compound is essential for tracing metabolic pathways, enabling precise quantification and visualization of glucose uptake, glycolysis, and other biochemical fluxes in research. It is a critical tool for scientists and researchers in pharmaceutical development, metabolic disease research, and biochemical tracer studies.

Application

• Metabolic Pathway Tracing: Used to study glycolysis, gluconeogenesis, and the pentose phosphate pathway in vitro and in vivo.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed as a radiolabeled tracer to investigate the metabolic fate of new drug candidates and their effects on host metabolism.
• Cell Biology & Biochemistry: Facilitates research into cellular energy utilization, insulin signaling, and glucose transporter (GLUT) function.
• Agricultural & Plant Science Research: Applied to study photosynthesis, carbon fixation, and sugar transport mechanisms in plants.
• Microbial Fermentation Studies: Used to track substrate utilization and metabolic output in bacterial and yeast cultures.
• Clinical Research: Supports investigations into diabetes, obesity, and cancer metabolism by providing a precise tracer for glucose disposal rates.

Basic Information

Item	Detail
Product Name	D-Glucose-Ul-14C
CAS No.	815-92-9
Molecular Formula	C6H12O6 (Uniformly labeled with 14C)
Molecular Weight	180.16 g/mol (unlabeled)
Synonyms	D-[U-14C]Glucose; [U-14C]-D-Glucose; Uniformly Labeled 14C-Glucose; Glucose (UL-14C); D-Glucose (Uniformly 14C Labeled); 14C-Glucose; Radiolabeled D-Glucose; Dextrose-UL-14C
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-Ul-14C is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to ensure high radiochemical purity, specific activity, and chemical identity. Certificates of Analysis (COA) detailing HPLC or TLC analysis, radiochemical purity, and specific activity are supplied with each shipment to meet the stringent requirements of research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider conditions recommended for radiolabeled compounds to minimize radiolytic decomposition.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR/HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC/TLC)	≥ 95% to ≥ 98%
Specific Activity	Customer specified (mCi/mmol)
Chemical Purity (HPLC)	≥ 98%
Solvent (if supplied as solution)	Ethanol/Water or specified aqueous buffer
Concentration	As per customer requirement (µCi/mL or mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.