Description

Lathosterol is a key intermediate sterol in the cholesterol biosynthesis pathway, specifically in the Kandutsch-Russell pathway. This high-purity compound is essential for research and development in pharmaceutical and biochemical applications, where precise control over sterol metabolism is required. It serves as a critical reference standard and starting material for scientists and manufacturers in the life sciences, nutraceutical, and advanced chemical synthesis sectors.

Application

• Pharmaceutical Research & Development: Used as a critical intermediate and reference standard in studies of cholesterol biosynthesis, metabolic disorders, and enzyme inhibition.
• Biochemical Assay Development: Serves as a substrate or standard in enzymatic assays for sterol metabolism, including for the enzyme lathosterol 5-desaturase (SC5D).
• Nutraceutical & Cosmetic Ingredient Synthesis: Acts as a precursor in the synthesis of specialized sterols and vitamin D analogs for high-value applications.
• Academic & Clinical Research: Essential for investigating lipid metabolism, Smith-Lemli-Opitz Syndrome (SLOS), and other inborn errors of cholesterol synthesis.
• Chemical Synthesis: A valuable building block for the synthesis of complex steroidal compounds and novel chemical entities.
• Quality Control Laboratories: Employed as an analytical reference standard for the identification and quantification of sterols in various matrices.

Basic Information

Product Name	Lathosterol
CAS No.	80-99-9
Molecular Formula	C27H46O
Molecular Weight	386.66 g/mol
Synonyms	5α-Cholest-7-en-3β-ol; (3β)-5α-Cholest-7-en-3-ol; 7-Dehydrocholesterol, 5α-; 5α-Cholest-7-en-3β-ol; δ7-Cholesten-3β-ol; Lathosterol; NSC 61799; 5α-Cholest-7-en-3-ol, (3β)-
EINECS	201-322-5

Quality Control

Our Lathosterol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and identity. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and consistent material, from research to process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	138°C - 142°C
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.