Description

Homatropine Methyl Bromide is a quaternary ammonium anticholinergic agent derived from tropane alkaloids. This compound is valued for its potent antimuscarinic properties, making it a key intermediate in the synthesis of specialized pharmaceutical actives. It is primarily sought by manufacturers in the pharmaceutical and fine chemical sectors for research and production. The material is supplied with a focus on high purity and batch-to-batch consistency to meet stringent industry requirements.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of antispasmodic and antisecretory drugs.
• Research Chemical: Used in biochemical and pharmacological research to study cholinergic receptor mechanisms.
• Fine Chemical Synthesis: Employed in the preparation of more complex quaternary ammonium compounds for various applications.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Homatropine Methyl Bromide
CAS No.	80-49-9
Molecular Formula	C17H24BrNO3
Molecular Weight	370.28 g/mol
Synonyms	Homatropine Methylbromide; Methylhomatropinium Bromide; Tropine Mandelate Methyl Bromide; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2-phenylacetate methyl bromide; Novatrin (historical brand name); Homatropine Methobromide; Mandelyltropine Methyl Bromide
EINECS	201-289-8

Quality Control

Our Homatropine Methyl Bromide is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to ensure reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.