Description

Methyl 3-Hydroxy-5-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester building block. This compound is critical for introducing the trifluoromethyl and phenolic hydroxyl functionalities into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, contributing to improved dielectric anisotropy and thermal stability in display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced solvent resistance and thermal properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a protected form of 3-hydroxy-5-(trifluoromethyl)benzoic acid for selective functionalization.

Basic Information

Product Name	Methyl 3-Hydroxy-5-(Trifluoromethyl)Benzoate
CAS No.	796119-63-6
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	3-Hydroxy-5-(trifluoromethyl)benzoic acid methyl ester; Methyl 3-hydroxy-5-(trifluoromethyl)benzoate; Benzoic acid, 3-hydroxy-5-(trifluoromethyl)-, methyl ester; 5-(Trifluoromethyl)resorcylic acid methyl ester; Methyl 5-(trifluoromethyl)-3-hydroxybenzoate; 3-Hydroxy-α,α,α-trifluoro-m-toluic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Hydroxy-5-(Trifluoromethyl)Benzoate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.