Description

R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis. Its value lies in its rigid, three-dimensional structure which is crucial for inducing high enantioselectivity in catalytic asymmetric reactions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel, optically pure active ingredients.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• As a key scaffold for organocatalysts used in enantioselective synthesis.
• As a building block for the synthesis of complex natural products and pharmaceutical intermediates.
• In the development of advanced materials, such as chiral polymers or liquid crystals with specific optical properties.
• For methodology research in academic and industrial laboratories exploring new catalytic systems.
• Potential use in the synthesis of agrochemicals requiring specific stereochemistry for optimal activity.

Basic Information

Product Name	R-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	791616-69-8
Molecular Formula	C40H30F6O2
Molecular Weight	632.66 g/mol
Synonyms	(R)-H8-BINOL-3,3'-di(4-trifluoromethylphenyl); (R)-3,3'-Bis(4-(trifluoromethyl)phenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol; R-3,3'-Di(4-trifluoromethylphenyl)-H8-BINOL; R-Octahydro-BINOL derivative with 4-CF3-phenyl groups; Chiral H8-BINOL ligand; Asymmetric catalyst ligand 791616-69-8
EINECS	Contact for details

Quality Control

Our production of this high-value chiral chemical adheres to strict quality protocols to ensure batch-to-batch consistency and optimal performance in sensitive catalytic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.