Description

4-Benzyloxy-2-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated aromatic building block, prized for its role in modulating the physicochemical properties of advanced molecules. This compound is essential for researchers and manufacturers requiring precise structural motifs to enhance metabolic stability, lipophilicity, and binding affinity in target compounds. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials for high-tech applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS, oncology, and inflammatory diseases.
• Agrochemical Development: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to improved biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Advanced Material Science: Employed in the production of specialty polymers and coatings that require specific thermal, chemical, or optical properties.
• Chemical Research & Development: A versatile building block for organic synthesis, cross-coupling reactions, and the exploration of new chemical entities in academic and industrial R&D labs.

Basic Information

Product Name	4-Benzyloxy-2-(Trifluoromethyl)Benzoic Acid
CAS No.	790695-23-7
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	2-(Trifluoromethyl)-4-(phenylmethoxy)benzoic Acid; Benzoic acid, 4-(benzyloxy)-2-(trifluoromethyl)-; 4-(Benzyloxy)-2-(trifluoromethyl)benzoic Acid; 4-Benzyloxy-α,α,α-trifluoro-o-toluic Acid; 4-(Phenylmethoxy)-2-(trifluoromethyl)benzoic Acid; 4-O-Benzyl-2-(trifluoromethyl)benzoic Acid; 790695-23-7 (CAS)
EINECS	Contact for details

Quality Control

Our production of 4-Benzyloxy-2-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.