Description

(S)-1,1,1-Trifluoro-2-Butylamine is a high-purity chiral amine building block characterized by its trifluoromethyl group and stereogenic center. This compound is of significant commercial interest due to the unique properties imparted by the fluorine atoms, which can dramatically influence the lipophilicity, metabolic stability, and binding affinity of final molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active pharmaceutical ingredients (APIs), and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disease drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine moiety enhances biological activity and environmental persistence.
• Asymmetric Catalysis: Serves as a chiral ligand or auxiliary in stereoselective synthesis to control the configuration of new stereocenters.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Fluorine Chemistry Studies: A valuable reference compound and starting material for academic and industrial research into organofluorine chemistry.

Basic Information

Product Name	(S)-1,1,1-Trifluoro-2-Butylamine
CAS No.	790617-82-2
Molecular Formula	C4H8F3N
Molecular Weight	127.11 g/mol
Synonyms	(S)-1,1,1-Trifluoro-2-aminobutane; (S)-2-Amino-1,1,1-trifluorobutane; (S)-α-Trifluoromethylpropylamine; (2S)-1,1,1-Trifluoro-2-butanamine; (S)-Trifluoro-sec-butylamine; (S)-TFBA; (S)-1,1,1-Trifluoro-sec-butylamine; (S)-2-Butylamine, 1,1,1-trifluoro-
EINECS	Contact for details

Quality Control

Our (S)-1,1,1-Trifluoro-2-Butylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.