Description

2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl CAS NO 787618-22-8 is a specialized, high-value organophosphorus ligand widely used in modern synthetic chemistry. Its primary value lies in its exceptional ability to facilitate challenging cross-coupling reactions, enabling the efficient synthesis of complex molecules. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high catalytic activity and selectivity.

Application

• Catalyst Ligand for Cross-Coupling Reactions: A key component in Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed C–N and C–C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enables the construction of complex heterocycles and active pharmaceutical ingredients (APIs) under mild conditions.
• Agrochemical Product Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Materials Science Research: Facilitates the creation of conjugated polymers and organic electronic materials through efficient coupling steps.
• Process Chemistry & Scale-Up: Employed in the development of robust, scalable manufacturing routes for high-value compounds.
• Academic & Industrial R&D: A critical tool for methodology development and exploring new chemical space in catalysis.

Basic Information

Product Name	2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl
CAS No.	787618-22-8
Molecular Formula	C30H43O2P
Molecular Weight	466.63 g/mol
Synonyms	RuPhos; 2-Dicyclohexylphosphino-2',6'-diisopropoxy-1,1'-biphenyl; Dicyclohexyl(2',6'-diisopropoxy[1,1'-biphenyl]-2-yl)phosphine; RuPhos Ligand; CataCXium® RuPhos; 787618-22-8; 2-(Dicyclohexylphosphino)-2',6'-diisopropoxybiphenyl
EINECS	Contact for details

Quality Control

Our 2-Dicyclohexylphosphino-2',6'-Diisopropoxybiphenyl is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, typically ≥97% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We adhere to cGMP principles where applicable, and our quality commitment ensures the material meets the stringent requirements for catalytic applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this product should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.