Description

3,5-Di-tert-Butyl-4-Methoxyphenylphosphine is a sterically hindered tertiary phosphine ligand, a key building block in advanced organometallic chemistry and catalysis. Its primary value lies in its ability to modulate the reactivity and selectivity of transition metal catalysts, particularly in challenging cross-coupling and hydrogenation reactions. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop more efficient synthetic routes.

Application

• As a ligand in homogeneous catalysis for cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
• As a key precursor in the synthesis of more complex phosphine ligands and metal-organic frameworks (MOFs).
• In pharmaceutical intermediate synthesis, where its steric bulk can improve reaction selectivity and yield.
• For academic and industrial R&D in developing new catalytic systems for fine chemical production.
• As a stabilizing agent for sensitive organometallic complexes.
• In the research and production of advanced materials, including OLEDs and electronic chemicals.

Basic Information

Product Name	3,5-Di-tert-Butyl-4-Methoxyphenylphosphine
CAS No.	782501-07-9
Molecular Formula	C15H25OP
Molecular Weight	252.34 g/mol
Synonyms	(3,5-Di-tert-butyl-4-methoxyphenyl)phosphine; DTBMPhosphine; 3,5-Di-tert-butyl-4-methoxybenzenephosphine; Phosphinous acid, P-(3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl)-; 3,5-Di-tert-butyl-4-methoxyphenylphosphane; DTBMPhos; Ligand DTBMPhos
EINECS	Contact for details

Quality Control

Our 3,5-Di-tert-Butyl-4-Methoxyphenylphosphine is manufactured under strict quality control protocols. Each batch is analyzed to ensure high purity and consistency, with specifications typically meeting or exceeding 98% purity by HPLC/NMR. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C for long-term stability. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.