Description

4-(Dibromomethyl)-3-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both dibromomethyl and fluorine substituents on a benzoic acid core, makes it a critical intermediate for introducing specific molecular complexity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and bromine atoms contribute to bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing complex organic molecules used in electronic displays and lighting technologies.
• Polymer Modification Agent: Employed to introduce functional groups into polymer chains, altering physical properties like solubility, thermal stability, or reactivity.
• Cross-Coupling Reactions: The dibromomethyl group can be utilized in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	4-(Dibromomethyl)-3-Fluorobenzoic Acid
CAS No.	777074-51-8
Molecular Formula	C8H5Br2FO2
Molecular Weight	311.93 g/mol
Synonyms	3-Fluoro-4-(dibromomethyl)benzoic Acid; Benzoic acid, 4-(dibromomethyl)-3-fluoro-; 4-(Dibromomethyl)-3-fluorobenzoic acid; 777074-51-8; 3-Fluoro-4-(dibromomethyl)benzoic acid; 4-(Dibromomethyl)-3-fluoro-benzoic acid; AKOS005258530; FT-07707451
EINECS	Contact for details

Quality Control

Our 4-(Dibromomethyl)-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.